Neural activity in the posterior superior temporal region during eye contact perception correlates with autistic traits
| Autor: | Shigeki Kameyama, Taro Endo, Toshiyuki Someya, Mutsuo Sasagawa, Naoya Hasegawa, Hiroatsu Murakami, Hideaki Kitamura, Jun Egawa |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Autism-spectrum quotient medicine.medical_specialty Adolescent genetic structures Brain activity and meditation Population Eye contact Audiology Eye Developmental psychology Young Adult medicine Humans Attention Autistic Disorder education Brain Mapping education.field_of_study Fusiform gyrus medicine.diagnostic_test General Neuroscience Magnetoencephalography Superior temporal sulcus Gaze Temporal Lobe Facial Expression Social Perception Female Psychology Photic Stimulation |
| Zdroj: | Neuroscience Letters. 549:45-50 |
| ISSN: | 0304-3940 |
| Popis: | The present study investigated the relationship between neural activity associated with gaze processing and autistic traits in typically developed subjects using magnetoencephalography. Autistic traits in 24 typically developed college students with normal intelligence were assessed using the Autism Spectrum Quotient (AQ). The Minimum Current Estimates method was applied to estimate the cortical sources of magnetic responses to gaze stimuli. These stimuli consisted of apparent motion of the eyes, displaying direct or averted gaze motion. Results revealed gaze-related brain activations in the 150–250 ms time window in the right posterior superior temporal sulcus (pSTS), and in the 150–450 ms time window in medial prefrontal regions. In addition, the mean amplitude in the 150–250 ms time window in the right pSTS region was modulated by gaze direction, and its activity in response to direct gaze stimuli correlated with AQ score. pSTS activation in response to direct gaze is thought to be related to higher-order social processes. Thus, these results suggest that brain activity linking eye contact and social signals is associated with autistic traits in a typical population. |
| Databáze: | OpenAIRE |
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