A Comparative Life Cycle Assessment between a Metered Dose Inhaler and Electric Nebulizer
| Autor: | Brandon Goulet, Brooke K. Mayer, Lars E. Olson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Engineering
life cycle assessment (LCA) metered dose inhaler (MDI) nebulizer chronic obstructive pulmonary disease (COPD) global warming potential (GWP) carbon dioxide (CO2) Geography Planning and Development TJ807-830 010501 environmental sciences Management Monitoring Policy and Law TD194-195 01 natural sciences Renewable energy sources 03 medical and health sciences 0302 clinical medicine Comparative life cycle assessment GE1-350 030212 general & internal medicine Mouthpiece 0105 earth and related environmental sciences Environmental effects of industries and plants Waste management Renewable Energy Sustainability and the Environment business.industry Inhaler Hfa 134a Metered-dose inhaler Environmental sciences Nebulizer business Global-warming potential |
| Zdroj: | Sustainability; Volume 9; Issue 10; Pages: 1725 Sustainability, Vol 9, Iss 10, p 1725 (2017) |
| ISSN: | 2071-1050 |
| DOI: | 10.3390/su9101725 |
| Popis: | Life cycle assessment (LCA) evaluates the environmental impact of a product based on the materials and processes used to manufacture the item as well as the item’s use and disposal. The objective of this LCA was to evaluate and compare the environmental impact of a metered dose inhaler, specifically the Proventil® HFA inhaler (Merk & Co., Inc., Kenilworth, NJ, USA), and an electric nebulizer, specifically the DeVilbiss Pulmo-Aide® nebulizer (DeVilbiss, Port Washington, NY, USA). GaBi LCA software was used to model the global warming potential (GWP) of each product by using substantiated data and well-justified assumptions for the components, manufacturing, assembly, and use of both devices. The functional unit used to model each device was one dose of the active drug, albuterol sulfate. The inhaler’s GWP, 0.0972 kg CO2-eq, was greater than the nebulizer’s even when uncertain parameters were varied ±100×. During the use phase ofa the inhaler, which accounted for approximately 96% of the inhaler’s total GWP, HFA 134a is used as a propellant to deliver the drug. The total GWP for the electric nebulizer was 0.0294 kg CO2-eq assuming that the mouthpiece was cleaned in a dishwasher, while it was 0.0477 kg CO2-eq when the nebulizer mouthpiece was hand washed between uses. The GWP breakeven scenario between dishwashing and hand washing occurred when the mouthpiece accounted for 10% of the dishwasher load. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|