Chronic Inflammatory Diseases and the Acute Respiratory Distress Syndrome (ARDS)
Autor: | Ana Fernandez-Bustamante, John E. Repine |
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Rok vydání: | 2014 |
Předmět: |
medicine.medical_specialty
ARDS Alcohol abuse Acute respiratory distress Pathogenesis Cigarette smoking Risk Factors Internal medicine Diabetes mellitus Drug Discovery Diabetes Mellitus medicine Animals Humans Obesity Intensive care medicine Inflammation Pharmacology Respiratory Distress Syndrome business.industry Smoking Respiratory disease medicine.disease Alcoholism Chronic Disease Disease Susceptibility business |
Zdroj: | Current Pharmaceutical Design. 20:1400-1408 |
ISSN: | 1381-6128 |
DOI: | 10.2174/13816128113199990561 |
Popis: | The Acute Respiratory Distress Syndrome (ARDS) is a highly fatal pro-inflammatory oxidative respiratory disease. Relatively recently, the modulating effects of chronic inflammatory processes on ARDS susceptibility have been recognized in a number of clinical studies. Herein, we briefly review some of the chronic conditions that have been reported to increase (cigarette smoking and alcohol abuse) or decrease (diabetes and obesity) susceptibility to ARDS. We also propose some potential pathways that may hold clues regarding the pathogenesis and/or therapy for ARDS. |
Databáze: | OpenAIRE |
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