Cranioplasty Using Autoclaved Autologous Skull Bone Flaps Preserved at Ambient Temperature
| Autor: | Kumar Lakshman, Rajeev Aravindakshan, Raymond Morris, Raju Paul Manjooran, Dominic Anto |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment ambient temperature Dentistry autologous skull bone flap Bone resorption 030218 nuclear medicine & medical imaging lcsh:RC321-571 storage 03 medical and health sciences 0302 clinical medicine medicine lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry business.industry General Neuroscience Osteomyelitis Retrospective cohort study medicine.disease Cranioplasty Surgery Skull medicine.anatomical_structure cranioplasty Original Article Decompressive craniectomy autoclaving Neurology (clinical) Neurosurgery Aseptic processing business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neurosciences in Rural Practice, Vol 08, Iss 04, Pp 595-600 (2017) Journal of Neurosciences in Rural Practice |
| ISSN: | 0976-3155 0976-3147 |
| DOI: | 10.4103/jnrp.jnrp_270_17 |
| Popis: | Context: Decompressive craniectomy followed by cranioplasty (CP) uses autologous craniectomy flaps or synthetic materials like titanium. Sterilization and preservation methods for the autologous bone flaps continue to be the surgeon's choice. Aim: This study aimed to assess the short-term as well as long-term clinical outcomes of CP using autoclaved autologous bone grafts. Settings and Design: This retrospective observational study was performed on patients admitted in a tertiary care teaching neurosurgery department. Patients and Methods: Seventy-two patients who underwent CP with autoclaved autologous skull flaps preserved under ambient conditions with strict aseptic precautions were included in the study. Statistical Analysis Used: Frequencies and percentages of the various characteristics before and after the surgery were tabulated. Continuous variables were summarized as means and standard deviations. Results: The primary CP had a satisfactory clinical outcome in 62 cases (86.11%). Osteomyelitis was observed in four patients (5.56%) nearly 2 months after the surgery. Radiologically significant bone resorption was noted in a single patient (1.39%) after 1 year. Five patients (6.94%) developed bone fragmentation or fracture, and the mean time taken for this was about 36 months. In all these ten cases, secondary CP was successfully done using a prefabricated, patient-specific titanium mesh. Conclusions: The efficacy and safety of the studied craniectomy flaps used for cranial reconstruction showed a good patient outcome. Further retrospective studies with larger cohorts and prospective case–control studies are essential so as to issue standard guidelines for sterilization and preservation of autologous bone flaps. |
| Databáze: | OpenAIRE |
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