Patterns of contrast enhancement in the pediatric spine at MR imaging with single- and triple-dose gadolinium
Autor: | Stacy Goergen, M. D. Dubin, John E. Jordan, L M Teresi, William G. Bradley, Dar-Yeong Chen, J. K. Tam, P. J. Pema |
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Rok vydání: | 1996 |
Předmět: |
Adult
Male medicine.medical_specialty Nerve root Adolescent Gadolinium Polyradiculoneuropathy chemistry.chemical_element Contrast Media Spinal Puncture Central nervous system disease Cerebrospinal fluid Heterocyclic Compounds medicine Organometallic Compounds Humans Radiology Nuclear Medicine and imaging Prospective Studies Spinal Cord Neoplasms Cerebellar Neoplasms Child Cerebrospinal Fluid medicine.diagnostic_test Guillain-Barre syndrome Lumbar puncture business.industry Brain Neoplasms Magnetic resonance imaging medicine.disease Spinal cord Magnetic Resonance Imaging Surgery medicine.anatomical_structure chemistry Spinal Cord Ependymoma Child Preschool Blood Vessels Female business Nuclear medicine Spinal Nerve Roots Medulloblastoma |
Zdroj: | Radiology. 198(1) |
ISSN: | 0033-8419 |
Popis: | To assess patterns of nerve root and spinal cord contrast enhancement in the pediatric spine at magnetic resonance (MR) imaging with single- and triple-dose gadolinium.In three control patients with no suspected pathologic spinal condition and 19 patients with a suspected condition, spinal cords were evaluated prospectively for potential spread of tumor to cerebrospinal fluid ("drop metastases") (n = 18) or Guillain-Barré syndrome (n = 1). After enhancement with 0.1 mmol/kg gadolinium, patients without definite drop metastases (n = 8) received a booster of 0.2 mmol/kg gadolinium 30-40 minutes later; clinical follow-up was obtained 12 1/2 to 19 months later.Drop metastases appeared as nodular areas of enhancement in 11 patients. Vascular enhancement related to the spinal cord surface and emerging nerve roots was observed in images obtained in all control patients, as well as in patients with negative findings at lumbar puncture and at clinical or MR imaging follow-up examination (n = 6). Vascular and nerve root enhancement increased with triple-dose gadolinium and was greater in patients after radiation therapy (n = 17) than in control patients (n = 3).Use of triple-dose gadolinium did not result in detection of additional cases of drop metastases. |
Databáze: | OpenAIRE |
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