Fractionation studies on the antigenic nature of Toxoplasma gondii

Autor:	John E. Faber, William A. Hook
Rok vydání:	1957
Předmět:	Antigenicity biology Immunology Toxoplasma gondii General Medicine Fractionation biology.organism_classification Complement fixation test In vitro Neutralization Microbiology Infectious Diseases Antigen parasitic diseases biology.protein Humans Parasitology Antibody Toxoplasma
Zdroj:	Experimental Parasitology. 6:449-458
ISSN:	0014-4894
DOI:	10.1016/0014-4894(57)90033-4
Popis:	Fractionation of Toxoplasma gondii suggested that both dye-test and complement-fixing antigenicity were related to protein material obtained from sonically fragmented cells by precipitation with 30% saturated ammonium sulfate at pH 7.O. This protein material was capable of neutralizing dye-test antibodies, acting as a complement-fixing antigen, and producing both complement-fixing and dye-test antibodies in guinea pigs. Carbohydrate from sonically fragmented toxoplasmas showed no antigenic activity in relation to the complement fixation or dye tests.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af04bfa730a0c2cb5608ad24bf93bde https://doi.org/10.1016/0014-4894(57)90033-4 Zobrazit plný text záznamu