Acquired hypertrichosis lanuginosa and malignancy. A clinical review and histopathologic evaluation with special attention to the 'mantle' hair of Pinkus
| Autor: | William F. Schorr, Stephen I. Hegedus |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Pathology
medicine.medical_specialty Hypertrichosis Dermatology Adenocarcinoma Malignancy Tongue Neoplasms Skin Manifestations medicine Humans Mantle (mollusc) Skin Internal malignancy Lanugo business.industry Acquired hypertrichosis lanuginosa General Medicine Middle Aged medicine.disease Adenocarcinoma Mucinous Distal third medicine.anatomical_structure Colonic Neoplasms Hormones Ectopic Androgens Female medicine.symptom business Hair |
| Zdroj: | Archives of dermatology. 106(1) |
| ISSN: | 0003-987X |
| Popis: | We record two cases of acquired hypertrichosis lanuginosa, bringing the total number of cases reported in the literature to nine. This sudden appearance of long, fine lanugo hair in an adult is a striking cutaneous sign of internal malignancy. From our study and review, this association with systemic cancer is even greater than a review of the literature would seem to indicate. Prominent red multiple papillae appearing the tip and distal third of the tongue appear to be an integral part of this syndrome. Two histologic features have not previously been reported. First, lanugo follicles extend almost parallel to the epidermal surface, deviating markedly from their normal near-vertical position. Second, many lanugo follicles are of the "mantle" type and contain lipidized cells within the mantle. |
| Databáze: | OpenAIRE |
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