Cool, Long Live
| Autor: | Xiangqi Li, Chaobao Zhang |
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| Přispěvatelé: | Xiangqi Li |
| Rok vydání: | 2013 |
| Předmět: | |
| DOI: | 10.5281/zenodo.884573 |
| Popis: | Traditional model suggested that low temperature promote longevity simply by a purely passive thermodynamic, not a genetic, process. However, a recent excellent investigation in Cell journal challenged this hypothesis, indicating that cold temperature actively increased lifespan via a genetic program of TRPA-1-responsed, calcium-sensitive signals transferring from PKC-2, SGK-1 to a wellknown lifespan regulator of DAF-16. This is very fascinating for lifespan extension, for we may achieve it via a simple cooling measure or taking a tablet if we will have developed a drug against that signaling pathway in the future. Editorial | Biohelikon : Cell Biology |
| Databáze: | OpenAIRE |
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