Biopsy Sites Suitable for the Diagnosis of Helicobacter pylori Infection and the Assessment of the Extent of Atrophic Gastritis
| Autor: | Toshio Fujioka, Takuya Takimoto, Hiroshi Kawata, Ken Kihira, Masaru Seki, Yushi Taniguchi, Toshichika Kojima, Kiichi Satoh, Koji Saifuku, Kenichi Ido, Kenkichi Tokumaru, Ken Kimura |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Gastritis Atrophic Male medicine.medical_specialty Pathology Helicobacter pylori infection Atrophic gastritis Biopsy Spirillaceae Gastroenterology Helicobacter Infections Internal medicine Gastroscopy Pyloric Antrum medicine Humans Aged Biopsy methods Helicobacter pylori Hepatology biology medicine.diagnostic_test business.industry Stomach Middle Aged bacterial infections and mycoses medicine.disease biology.organism_classification Female Histopathology Gastritis medicine.symptom business |
| Zdroj: | American Journal of Gastroenterology. 93:569-573 |
| ISSN: | 0002-9270 |
| Popis: | We performed this study to determine which biopsy sites in the stomach are suitable for the diagnosis of Helicobacter pylori infection and the assessment of the extent of atrophic gastritis.Endoscopy was performed in 76 H. pylori-positive patients with histologically confirmed chronic gastritis. Biopsies were taken from the following six sites: the lesser curvatures of the mid-antrum (site 1), the angulus (site 2), the middle body (site 3), and the greater curvatures of the mid-antrum (site 4), the angulus (site 5), and the middle body (site 6) of the stomach. The extent of atrophic gastritis was assessed endoscopically as well as histologically, and patients were classified into five groups according to its extent. H. pylori status was assessed histologically. The histological severity of inflammation, activity, atrophy, and intestinal metaplasia was assessed according to the Updated Sydney System. The grades of these items were compared among the six biopsy sites in each group of patients.Site 6 was most reliable for the diagnosis of H. pylori infection, and site 4 was suitable for examining the status of H. pylori colonization in the antrum. Site 1, site 3, and site 6 were suitable for the assessment of the extent of atrophic gastritis.Our results indicate that for an accurate diagnosis and assessment, biopsies should be taken from the following four sites: the lesser curvatures of the mid-antrum (site 1) and middle body (site 3), and the greater curvatures of the mid-antrum (site 4) and middle body (site 6) of the stomach. |
| Databáze: | OpenAIRE |
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