Incidental diagnosis of paragonimiasis after histopathological examination of cholecystectomy specimen in Nepal: A case report
| Autor: | Pearlbiga Karki, Manoj Khadka, Gayatri Karki, Jung Bahadur Thapa, Pinky Jha, Prabesh Karki, Gaurab Mainali |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Abdominal pain Paragonimiasis medicine.medical_treatment Paragonimus Case Report Praziquantel 03 medical and health sciences 0302 clinical medicine Nepal Gall bladder Biopsy Medicine Medical history biology medicine.diagnostic_test business.industry Gallbladder General Medicine biology.organism_classification medicine.disease Dermatology medicine.anatomical_structure 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Cholecystectomy medicine.symptom business Rare disease |
| Zdroj: | Annals of Medicine and Surgery |
| ISSN: | 2049-0801 |
| DOI: | 10.1016/j.amsu.2021.02.016 |
| Popis: | Introduction Paragonimiasis or lung fluke disease is a typical food-borne parasitic zoonosis caused by infection with Paragonimus species. The Paragonimus is a trematode that mainly infects the lungs of humans after eating an infected raw or undercooked crab or crayfish. Case presentation Herein we report a case of peritoneal Paragonimiasis in the gallbladder of a 58-year-old female from Rukum district of Nepal. It was an incidental diagnosis following routine histopathological examination of the cholecystectomy specimen. She presented with the symptoms of abdominal pain, fever, cough, and had a history of consumption of partially cooked river crabs. She responded well to praziquantel and improved thereafter. Clinical discussion Ectopic paragonimiasis is a rare disease and it presents with few clinical symptoms so it is significantly difficult to make a diagnosis and treat the patients. Even if a sputum test and biopsy are performed, the ova or body of Paragonimus parasites may not be detectable due to insufficient amount of specimens. Therefore, thorough history taking should be given importance. The dietary history of partially cooked crab or crayfish should indicate towards a high suspicion of Paragonimiasis. Any such indication should be immediately confirmed, which in our case was done by routine histopathological examination of the cholecystectomy specimen. Conclusion We report the case of a patient with peritoneal paragonimiasis in the gallbladder. Ectopic paragonimiasis is hard to diagnose due to an ignorance of, misdiagnosis, and the rarity of this disease. Thus, thorough history-taking and clinical suspicion of parasitic infection is essential. Highlights • Paragonimiasis is a parasitic zoonosis caused by Paragonimus species due to consumption of raw/partially cooked crustaceans. • Paragonimiasis mainly infects the lungs of humans but ectopic sites like the brain and peritoneum are also seen. • Ectopic paragonimiasis is hard to diagnose due to an ignorance of, misdiagnosis, and the rarity of this disease. • Thorough history-taking and clinical suspicion of parasitic infection is essential for diagnosis of Paragonimiasis. • Gallbladder histopathology after elective cholecystectomy helps in incidental diagnosis of many diseases like Paragonimiasis. |
| Databáze: | OpenAIRE |
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