Nano drug delivery strategy of 5-fluorouracil for the treatment of colorectal cancer
| Autor: | Satheesh Natarajan, Suriyakala Perumal Chandran, Sowmiya Chandraseharan, Masliza Suhaini Binti Mohd Shahimi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Cultural Studies
Oncology Linguistics and Language History medicine.medical_specialty Colorectal cancer medicine.medical_treatment Rectum 02 engineering and technology 010402 general chemistry 01 natural sciences lcsh:RC254-282 Language and Linguistics Targeted therapy Internal medicine medicine 5-fluorouracil Stage (cooking) Chemotherapy Nano drug delivery business.industry 021001 nanoscience & nanotechnology medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Silica nanoparticles digestive system diseases 0104 chemical sciences Radiation therapy medicine.anatomical_structure Fluorouracil Anthropology Nano Drug Delivery Nanoparticles 0210 nano-technology business medicine.drug |
| Zdroj: | Journal of Cancer Research and Practice, Vol 4, Iss 2, Pp 45-48 (2017) |
| ISSN: | 2311-3006 |
| DOI: | 10.1016/j.jcrpr.2017.02.002 |
| Popis: | Colorectal cancer (CRC) is the leading cause of cancer-related mortality, annually responsible for around 655,000 deaths worldwide. CRC usually develops very slowly, over a period of 10 to 20 years and typically begin as a non-cancerous polyp that develops on the inner layer of the colon or rectum. However, CRC is curable if detected at an early stage. The current treatment of colorectal cancer primarily depends on surgery, chemotherapy, radiotherapy and targeted therapy. A combination of two or more treatments is often recommended to achieve the best outcome, depending on the stage of cancer development. In this review, we summarized the challenges of using 5-Fluorouracil as chemotherapy to treat colorectal cancer, and discussed the implications of nano drug delivery system for improved therapeutic outcome of 5-Flurouracil. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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