Mutagenicity of smoke condensate of bidi — an indigenous cigarette of India
| Autor: | Lata P. Shirname, Shrirang S. Pakhale, Sumati V. Bhide, Malini M. Menon |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
Cancer Research Salmonella India medicine.disease_cause Chinese hamster Mice chemistry.chemical_compound Cricetulus Cricetinae Smoke Tobacco medicine Animals Mutation biology urogenital system Azaguanine General Medicine biology.organism_classification Molecular biology Plants Toxic medicine.anatomical_structure chemistry 8-Azaguanine Bone marrow Mutagens |
| Zdroj: | Carcinogenesis. 5:1179-1181 |
| ISSN: | 1460-2180 0143-3334 |
| DOI: | 10.1093/carcin/5.9.1179 |
| Popis: | The possible mutagenicity of bidi smoke condensate (BSC), an indigenous form of an Indian cigarette has been studied using three short-term test systems. It was seen that BSC caused frame-shift mutations in Salmonella typhimurium strains TA 98 and TA 1538 and required metabolic activation. In the mammalian test systems, BSC induced 8 azaguanine resistant mutations in V79 Chinese hamster cells in the presence of S9 mixture and induced elevated frequencies of micronucleated erythrocytes in the bone marrow of Swiss mice. |
| Databáze: | OpenAIRE |
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