Predictors of depressive symptoms at hospital discharge in patients with major depressive disorder

Autor: Ivan W. Miller, Lauren M. Weinstock, Gary Epstein-Lubow, Michelle M. Wedig
Rok vydání: 2013
Předmět:
Zdroj: International Journal of Psychiatry in Clinical Practice. 17:144-147
ISSN: 1471-1788
1365-1501
DOI: 10.3109/13651501.2013.777746
Popis: Often patients with major depressive disorder (MDD) leave the hospital with continued significant symptomatology. This study sought to evaluate demographic, clinical, and psychosocial predictors of the presence of clinically significant depressive symptoms, defined as a Modified Hamilton Rating Scale for Depression score of ≥ 14, immediately following hospitalization for MDD.The study enrolled 135 patients with MDD as part of a larger clinical trial investigating the efficacy of post-hospitalization pharmacologic and psychosocial treatments for depressed inpatients. Structured clinical interview and self-report data were available from 126 patients at hospital admission and discharge.Despite the significant decreases in depressive symptoms over the course of hospitalization, 91 (72%) displayed clinically significant depressive symptoms at discharge. Multivariate logistic regression analysis revealed that female sex, earlier age of onset, and poorer social adjustment were unique predictors of symptom outcome.Results suggest that a large proportion of patients leave the hospital with continued significant symptomatology, and the presence of such symptoms following hospitalization for MDD is likely to be explained by a combination of factors.
Databáze: OpenAIRE
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