Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major

Autor:	Mauro M. Teixeira, Luís Carlos Crocco Afonso, Daniele G. Souza, Fernanda Oliveira Ferraz, Luiz Antônio Rodrigues de-Freitas, Ricardo T. Gazzinelli, Leda Quercia Vieira, Helton C. Santiago, Luciana Santiago, Carolina F. Oliveira
Jazyk:	angličtina
Rok vydání:	2004
Předmět:	Chemokine Immunology Leishmaniasis Cutaneous Biology Microbiology CCL5 Mice stomatognathic system Immunity parasitic diseases medicine Animals Leishmania major Chemokine CCL5 Mice Inbred BALB C Kinetoplastida virus diseases Leishmaniasis hemic and immune systems biology.organism_classification medicine.disease Blockade Mice Inbred C57BL stomatognathic diseases Infectious Diseases biology.protein Protozoa Parasitology Fungal and Parasitic Infections
Zdroj:	Repositório Institucional da UFOP Universidade Federal de Ouro Preto (UFOP) instacron:UFOP ResearcherID
Popis:	The expression and putative role of chemokines during infection with Leishmania major in mice were investigated. CCL5 expression correlates with resistance, and blockade of CCL5 rendered mice more susceptible to infection. CCL5 is part of the cascade of events leading to efficient parasite control in L. major infection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acb44c8619727d749ae13ca55dc7f5a http://www.repositorio.ufop.br/handle/123456789/7962 Zobrazit plný text záznamu