Intermittent individual housing increases survival of newly proliferated cells
Autor: | Stefan Brené, Mieke C. Zwart, Therese M. Pham, Vera Baumans, Elin Åberg |
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Rok vydání: | 2005 |
Předmět: |
Neurons
Mice Inbred BALB C Cell Survival General Neuroscience Dentate gyrus Neurogenesis Hippocampus Stimulating environment Motor Activity Housing Animal Andrology Mice chemistry.chemical_compound Bromodeoxyuridine chemistry Corticosterone Physical Conditioning Animal Dentate Gyrus Animals Environment Design Female Psychology Neuroscience Cell Division |
Zdroj: | NeuroReport. 16:1419-1422 |
ISSN: | 0959-4965 |
DOI: | 10.1097/01.wnr.0000177013.29355.e0 |
Popis: | In this study, we analyzed how intermittent individual housing with or without a running wheel influenced corticosterone levels and survival of newly proliferated cells in the dentate gyrus of the hippocampus. Female Balb/c mice, in standard or enhanced housing, were divided into groups that were individually housed with or without running wheels on every second day. Intermittent individual housing without, but not with, running wheels increased survival of proliferated cells in the dentate gyrus as compared with continuous group housing in standard or enhanced conditions. Thus, changes in housing conditions on every second day can, under certain circumstances, have an impact on the survival of newly proliferated cells in the dentate gyrus. |
Databáze: | OpenAIRE |
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