Resposta imune e capacidade de neutralização de anticorpos produzidos em ovinos jovens imunizados com veneno de Crotalus durissus terrificus nativo e irradiado com Cobalto 60
| Autor: | Rui Seabra Ferrreira Junior, Janaína Baptista Alves, Renata Couto, Benedito Barraviera, Domingos Alves Meira, Nanci do Nascimento |
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| Přispěvatelé: | Universidade Estadual Paulista (Unesp), Instituto de Pesquisas Energéticas e Nucleares (IPEN) |
| Jazyk: | portugalština |
| Rok vydání: | 2009 |
| Předmět: |
Antiserum
Crotalic antiserum Ovis aries Crotalus Durissus Terrificus Venom General Veterinary Soro anticrotálico Production cost Significant difference Biology Crotalus durissus terrificus Ovis Microbiology Ovinos Hyperimmunization Hipermunização Antibody Profile Ovines Animalia Irradiation lcsh:Animal culture Envenomation Irradiação lcsh:SF1-1100 |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Brazilian Journal of Veterinary Research and Animal Science, Vol 46, Iss 3 (2009) |
| Popis: | Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:24:33Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:41:13Z : No. of bitstreams: 1 2-s2.0-78149421826.pdf: 1381462 bytes, checksum: de9ad9d0b3960645486c36dca048dc3c (MD5) Made available in DSpace on 2014-05-27T11:24:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-01 The ELISA technique was used to evaluate and compare young ovine humoral immune response during crotalic antiserum production. Animals were clinically evaluated throughout this process, and the neutralizing capacity of antisera raised against natural (NV) and Cobalt-60 irradiated (IrV) venoms of Crotalus durissus terrificus (C.d.t.) was verified by means of in vitro challenges. Three groups of six animals each were used: G1 received NV; G2 was inoculated with IrV; and G3 was used as control. Animals received six immunizations during 84 days at 14-day intervals. ELISA of antibody profile showed significant difference (p |
| Databáze: | OpenAIRE |
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