Intermediate to long-term follow-up indicates low risk of recurrence after Double HIT endoscopic treatment for primary vesico-ureteral reflux
| Autor: | Scott Cuda, Jonathan F. Kalisvaart, Andrew J. Kirsch, Jonathan D. Kaye, Hal C. Scherz |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Voiding cystourethrogram Adolescent Urology Urinary system Injections Intralesional Risk Assessment Asymptomatic Cohort Studies Secondary Prevention Ureteroscopy medicine Humans Prospective Studies Hyaluronic Acid Child Prospective cohort study Vesico-Ureteral Reflux medicine.diagnostic_test business.industry Reflux Infant Dextrans Ultrasonography Doppler Prostheses and Implants Surgery Endoscopy Treatment Outcome Child Preschool Pediatrics Perinatology and Child Health Female Dextranomer medicine.symptom Tomography X-Ray Computed business Follow-Up Studies medicine.drug Cohort study |
| Zdroj: | Journal of Pediatric Urology. 8:359-365 |
| ISSN: | 1477-5131 |
| DOI: | 10.1016/j.jpurol.2011.07.006 |
| Popis: | Purpose Follow-up of patients undergoing dextranomer/hyaluronic acid injection for vesico-ureteral reflux (VUR) is controversial. The purpose of our study was to test the hypothesis that patients undergoing the double hydrodistention‒implantation technique (Double HIT) have a higher clinical and radiographic success rate. Materials and methods Patients undergoing Double HIT endoscopic injection for VUR were prospectively identified. Patients underwent an ultrasound at 6 weeks to assess the implants, and, if visible, prophylactic antibiotics were discontinued and patients were scheduled for a 1-year voiding cystourethrogram (VCUG). Radiographic success was defined as a negative VCUG and clinical success as no febrile urinary tract infections at 1 year. Results A total of 54 patients underwent endoscopic injection for VUR. Twenty-five (51%) were compliant with the 1 year follow-up; 18 non-compliant patients were contacted and their clinical status assessed. Thirty patients eventually completed the 1-year VCUG at a mean of 12.2 months (range 10–20). Among the 60% of patients with 1-year radiographic follow-up, 2 had persistent VUR for a radiologic success rate of 93%. All radiographic failures were infection-free. Of the 80% (43/54) of patients with available clinical data, 3 (7%) had afebrile UTI for a clinical success rate of 93%. Conclusions The Double HIT leads to a 93% clinical and 93% radiographic intermediate/long-term success rate. With this technique, better outcomes were achieved with fewer recurrences than previously reported. These favorable results challenge the need for postoperative VCUG in asymptomatic patients after the Double HIT. |
| Databáze: | OpenAIRE |
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