Electroacupuncture for post-stroke overactive bladder: a multi-centre pilot randomized controlled trial
| Autor: | Hai-Yong Chen, Wai Yin Tsang, Kwok P. Leung, Bacon F.L. Ng, Lo Lo Yam, Changde Wang, Wing Lok Lam, Eric Ziea, Min-Jie Zhou, Lixing Lao, Sheung Wai Li, Wing Fai Yeung, Pui Yan Chan |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Electroacupuncture medicine.medical_treatment Urination Pilot Projects Traditional Chinese medicine law.invention Randomized controlled trial law medicine Acupuncture Humans Multi centre Stroke Aged Aged 80 and over business.industry Urinary Bladder Overactive General Medicine Middle Aged medicine.disease Treatment Outcome Complementary and alternative medicine Overactive bladder Physical therapy Post stroke Female Neurology (clinical) business |
| Zdroj: | Acupuncture in medicine : journal of the British Medical Acupuncture Society. 39(3) |
| ISSN: | 1759-9873 |
| Popis: | Background Although acupuncture has been shown to be effective at treating overactive bladder (OAB) following stroke, to our knowledge, no randomized controlled trial (RCT) examining the effects of acupuncture on patients with post-stroke OAB has been conducted. The aim of this preliminary study was to explore the effects of electroacupuncture (EA) in the treatment of post-stroke OAB. Methods This study was a multi-site randomized, assessor-blind, controlled pilot trial of patients with post-stroke OAB. In all, 34 post-stroke subjects (mean age: 71.0 years; 32.4% female) with OAB symptoms were randomly assigned to the treatment group or control group in a 1:1 ratio. The subjects in the treatment group were treated with six sessions of EA for 4 weeks, while the subjects in the control group received usual care. The primary outcome measure was the overactive bladder symptom scale (OABSS). Secondary outcome measures included a three day bladder diary and the stroke-specific quality-of-life scale (SSQoL). Results EA showed a moderate effect size (ES) on the perceived severity of OAB symptoms as measured by the OABSS at week 5 (one week post-treatment, ES 0.57; p = 0.034) and week 8 (three weeks post-treatment, ES 0.60; p = 0.021), although the results did not remain statistically significant after Bonferroni correction for multiple testing. No significant differences in bladder diary parameters or SSQoL score were found. The EA treatment was well tolerated by the post-stroke subjects. Conclusion A six-session EA treatment was feasible and appeared to reduce OAB symptoms in post-stroke patients. Further fully powered trials are warranted to confirm the efficacy of EA for those with post-stroke OAB. |
| Databáze: | OpenAIRE |
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