Pelvic Protection Limiting Lower Limb Flail Reduces Mortality
| Autor: | Diagarajen Carpanen, Thuy-Tien N. Nguyen, Alastair Darwood, J C Clasper, Spyros D. Masouros, Iain A Rankin |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
0211 other engineering and technologies Biomedical Engineering 02 engineering and technology Blast injury Lower limb Pelvis Mice 03 medical and health sciences 0302 clinical medicine Blast Injuries Physiology (medical) medicine Animals Humans 021110 strategic defence & security studies business.industry Incidence (epidemiology) 030208 emergency & critical care medicine Limiting medicine.disease Confidence interval body regions Relative risk Anesthesia Pelvic fracture Cadaveric spasm business |
| Zdroj: | Journal of Biomechanical Engineering. 143 |
| ISSN: | 1528-8951 0148-0731 |
| Popis: | Pelvic blast injury is one of the most severe patterns of injury to be sustained by casualties of explosions. We have previously identified the mechanism of injury in a shock tube-mediated murine model, linking outward flail of the lower limbs to unstable pelvic fractures and vascular injury. As current military pelvic protection does not protect against lower limb flail, in this study we have utilized the same murine model to investigate the potential of novel pelvic protection to reduce injury severity. Fifty cadaveric mice underwent shock-tube blast testing and subsequent injury analysis. Pelvic protection limiting lower limb flail resulted in a reduction of pelvic fracture incidence from both front-on (relative risk (RR) 0.5, 95% confidence intervals (CIs) 0.3–0.9, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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