Only few benefits from propylene glycol drench in early lactation for cows identified as physiologically imbalanced based on milk spectra analyses
Autor: | Beatriz Sanz Bernardo, Mogens Krogh, Cinzia Marchitelli, Victor Henrique Oliveira, Clément Grelet, Alessandra Crisà, Frédéric Dehareng, Miel Hostens, Dirk Werling, Tine Rousing, Federica Signorelli, Nina Dam Otten, Leslie Foldager, Soren Ostergaard |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Isocitrates
Disease occurrence media_common.quotation_subject Denmark Malates Ice calving Glutamic Acid Biology 03 medical and health sciences Milk yield Animal science Lactation Spectroscopy Fourier Transform Infrared Genetics medicine Animals Prospective Studies 030304 developmental biology media_common 0303 health sciences 3-Hydroxybutyric Acid Dairy herds Reproduction milk biomarker dairy cow 0402 animal and dairy science food and beverages 04 agricultural and veterinary sciences Milk Proteins 040201 dairy & animal science Propylene Glycol physiological and metabolic imbalance medicine.anatomical_structure Milk propylene glycol Animal Science and Zoology Cattle Female After treatment Food Science |
Zdroj: | Østergaard, S, Krogh, M A, Oliveira, V H S D, Larsen, T, GplusE Consortium & Otten, N D 2020, ' Only few benefits from propylene glycol drench in early lactation for cows identified as physiologically imbalanced based on milk spectra analyses ', Journal of Dairy Science, vol. 103, no. 2, pp. 1831-1842 . https://doi.org/10.3168/jds.2019-17205 |
Popis: | The main objective of this study was to test the efficiency of a management system combining metabolic clustering of cows based on Fourier-transform mid-infrared (FT-MIR) spectra of milk and targeted treatment of metabolically imbalanced cows with propylene glycol drench. We hypothesized that cows identified in a metabolically imbalanced status during early lactation were associated with subsequent impaired health, reproduction, and production, and that treatment with propylene glycol treatment would improve health, reproduction, and production relatively more in these cows than in control cows. We completed a prospective, randomized controlled trial with 356 early-lactation cows in 2 private dairy herds in Denmark from December 2017 to April 2018. Milk samples of cows were collected before treatment, from 4 to 9 d in milk, and after treatment, from 22 to 27 d in milk. Milk samples were analyzed using FT-MIR spectroscopy. We also measured 4 milk metabolites (β-hydroxybutyrate, isocitrate, malate, and glutamate) and fat and protein contents. Based on FT-MIR spectra and cluster analyses, cows were clustered into groups of metabolically imbalanced and healthy cows. Within each group, cows were allocated randomly to treatment with propylene glycol (500 mL for 5 d) or no treatment. We analyzed the effect of the treatment on cow-level variables: metabolic cluster, milk metabolites, fat and protein contents, and fat-to-protein ratio at a milk sampling after the treatment. Furthermore, we analyzed daily milk yield, calving to first service interval, and disease occurrence. Results showed only a few effects of propylene glycol treatment and few interactions between treatment and metabolic clusters. We found no significant main effects of propylene glycol treatment in any of these analyses. A negative effect of the imbalanced metabolic cluster was found for the outcome of calving to first service interval for multiparous cows. In conclusion, we found a longer calving to first service interval in metabolically imbalanced cows, but we were not able to demonstrate overall benefits from the applied detection of cows in imbalanced metabolic status in early lactation and follow-up by treatment with propylene glycol. |
Databáze: | OpenAIRE |
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