Lethal acute liver failure in a patient treated with sunitinib

Autor:	M Meijer, F E de Jongh, S S Guillen
Rok vydání:	2016
Předmět:	Male Oncology medicine.medical_specialty Indoles Stromal cell medicine.drug_class Fulminant urologic and male genital diseases Article Tyrosine-kinase inhibitor 03 medical and health sciences Fatal Outcome 0302 clinical medicine Renal cell carcinoma Internal medicine Sunitinib medicine Carcinoma Humans Pyrroles 030212 general & internal medicine Neoplasm Metastasis Carcinoma Renal Cell Protein Kinase Inhibitors Aged business.industry Acute kidney injury Liver failure General Medicine Acute Kidney Injury Liver Failure Acute medicine.disease Kidney Neoplasms female genital diseases and pregnancy complications 030220 oncology & carcinogenesis Cancer research business medicine.drug
Zdroj:	BMJ Case Reports. :bcr2015213624
ISSN:	1757-790X
DOI:	10.1136/bcr-2015-213624
Popis:	Sunitinib is a tyrosine kinase inhibitor that is used as an anticancer drug in renal cell carcinoma (RCC), pancreatic neuroendocrine tumours (PNETs) and gastrointestinal stromal tumour. Elevated liver enzymes are frequently observed during treatment but acute liver failure is uncommon. We describe a case of fulminant acute liver failure and acute kidney injury during treatment with sunitinib for metastatic RCC.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab9d013d4d97af4b39c863989dccfbc https://doi.org/10.1136/bcr-2015-213624 Zobrazit plný text záznamu