Aluminium nitride based BIO-MEMS for vascular graft monitoring
| Autor: | Francesco Rizzi, Francesco Guido, Antonio Qualtieri, Salvatore Puce, Lara Natta, R. Pulli, Luciana Algieri, Vincenzo Mastronardi, Filippo Pisano, M. De Vittorio |
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| Přispěvatelé: | Natta, L., De Vittorio, M., Mastronardi, V. M., Guido, F., Algieri, L., Puce, S., Pisano, F., Rizzi, F., Pulli, R., Qualtieri, A. |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Microelectromechanical systems
0303 health sciences Prosthetic graft Biocompatibility Computer science Aluminium nitride Mem 02 engineering and technology Vascular graft 021001 nanoscience & nanotechnology Flexible electronic Piezoelectric material Flexible electronics 03 medical and health sciences chemistry.chemical_compound chemistry Bio-MEMS 0210 nano-technology Aluminum nitride 030304 developmental biology Biomedical engineering |
| Popis: | Various techniques are able to monitor the hemodynamic conditions inside a prosthetic graft, thus providing useful information information to optimise patient’s therapy but even on the graft status. However, all the current technologies affect the mechanical properties and functionality of the device. A proof-of-concept experiment is reported in this paper, which demonstrates the ability of an A1N-based sensor, integrated on the extraluminal surface of the prosthesis, to continuously monitor the inner blood flow, avoiding any interference with the graft structure. To this aim, mechanical properties and dimensions of the sensor are optimized in order to maximize its response to a variation of hemodynamics parameters. The very performing features of the sensor in terms of sensitivity, conformability and biocompatibility of the used materials, make the device able to successfully monitor the graft functionality, opening new perspectives for the development of an implantable sensorized vascular graft system. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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