Plasma Renin Activity, Blood Uric Acid and Plasma Volume in Pregnancy-Induced Hypertension
| Autor: | I. Desailly, Pleskov L, Carayon A, E. Comoy, J.F. de Fremont, P. Fievet, Coevoet B, Boulanger Jc, P. Verhoest, J.E. Demory |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
medicine.medical_specialty Blood uric acid Aldosterone business.industry Pregnancy Complications Cardiovascular urologic and male genital diseases Plasma volume Plasma renin activity Uric Acid chemistry.chemical_compound Endocrinology chemistry Pregnancy Internal medicine Hypertension Renin Plasma concentration medicine Humans Pregnancy induced Female Plasma Volume business |
| Zdroj: | Nephron. 40:429-432 |
| ISSN: | 2235-3186 1660-8151 |
| DOI: | 10.1159/000183513 |
| Popis: | Plasma renin activity (PRA), plasma aldosterone (PA), blood uric acid (BUA), plasma concentrations of catecholamines (Pcat) and plasma volume (PV) were measured simultaneously in 24 patients with pregnancy-induced hypertension. This hypertensive group was divided into labile (LH) and permanent hypertension (PH) groups according to the response of their blood pressure to home bed rest. As compared to normal theoretical values, PV was decreased in both hypertensive groups (LH = -70%; PH = -14%). As compared to a control group of 16 normotensive pregnant women, PRA was higher in LH and lower in PH whereas PA was lower in both hypertensive groups. In both hypertensive groups, BUA was higher than in the control group. No difference in Pcat was found between the three groups. In the PH group negative correlations were found between BUA and PRA, as well as between BUA and PV, but no correlation between PRA and PV nor between Pcat and BUA were found.LH and PH are two pathophysiologically different entities in pregnancy-induced hypertension. In PH, renin secretion is not appropriate to hypovolemia and therefore not primarily involved in the pathogenesis of hypertension. The role of hypovolemia in the increase of BUA may be discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|