Constant Light Extends Life in Hamsters with Heart Disease
| Autor: | Walter N. Tapp, Jennifer L. Gross, Susan D. Drastal, John E. Ottenweller, Benjamin H. Natelson |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Heart Failure
Male photoperiodism medicine.medical_specialty Light Artificial light Heart disease business.industry Longevity Physiology Organ Size Darkness medicine.disease General Biochemistry Genetics and Molecular Biology Surgery Cricetinae Heart failure Testis Animals Medicine Cardiomyopathies business Constant light |
| Zdroj: | Experimental Biology and Medicine. 202:69-74 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-202-43513 |
| Popis: | Our previous work has shown that constant light can prolong the life of hamsters with heart disease. Although we have seen this result several times, constant light was not protective in our most recent experiment. We undertook this study because we had changed some conditions. As in previous experiments, we found that life in constant light extended life for cardiomyopathic hamsters as compared with others living in a 12:12-hr light:dark environment. A second factor affecting survival was the number of hamsters in a group. Hamsters housed in groups of five lived longer than those housed in groups of two under the same lighting conditions. Data from one experiment suggested that a short photoperiod (6:18 light:dark) was also protective. Although these experiments indicate that the protective effects of different light:dark schedules are not simple ones, they are important because their use may prove to be a helpful adjunct in the treatment of congestive heart failure. |
| Databáze: | OpenAIRE |
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