Dermatomyositis, clinically presenting with cutaneous ulcers, with histopathologic evidence of perforating collagenosis
| Autor: | Rachel K. Rosenstein, Andrew G. Franks, Mitalee P Christman, Kathryn J. Martires, Vitaly Terushkin, Nicole Seminara, Shane A Meehan, Brian D Golden |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Pathology business.industry Dermatology General Medicine Dermatomyositis medicine.disease Pathophysiology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Cutaneous ulcers 030220 oncology & carcinogenesis Diabetes mellitus medicine Chronic renal failure Vasculitis business |
| Zdroj: | Rosenstein, Rachel; Martires, Kathryn; Christman, Mitalee; Terushkin, Vitaly; Meehan, Shane A; Seminara, Nicole; et al.(2016). Dermatomyositis, clinically presenting with cutaneous ulcers, with histopathologic evidence of perforating collagenosis. Dermatology Online Journal, 22(12). Retrieved from: http://www.escholarship.org/uc/item/6qd0q51w |
| Popis: | Dermatomyositis is a systemic, autoimmune diseasewith a variety of clinical features that often includemyositis and characteristic cutaneous findings. Asubset of patients with dermatomyositis developcutaneous ulcers, often in the setting of vasculitis orvasculopathy. We present a case of dermatomyositiswith cutaneous ulcers that show perforatingcollagenosis on histopathologic examination.Acquired reactive perforating collagenosistypically occurs in the setting of diabetes mellitus,chronic renal failure, and other pruritic conditions,and this case represents a rare association withdermatomyositis, which may ultimately be helpful inelucidating the pathophysiology of this perforatingdisorder. |
| Databáze: | OpenAIRE |
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