Clearance of Immunodeficiency-associated Vaccine-derived Poliovirus Infection With Pocapavir

Autor:	Sabelle Jallow, Brian Eley, Wonita Petersen, Marc S. Collett, Lerato Seakamela, Shelina Moonsamy, Wayne Howard, Melinda Suchard, Jeffrey R. Hincks, Julie Copelyn, Jo M. Wilmshurst
Rok vydání:	2020
Předmět:	Microbiology (medical) Male Investigational drug medicine.disease_cause Antiviral Agents 03 medical and health sciences Feces 0302 clinical medicine Agammaglobulinemia 030225 pediatrics medicine Humans 030212 general & internal medicine Immunodeficiency business.industry Poliovirus Phenyl Ethers Infant Genetic Diseases X-Linked Drugs Investigational medicine.disease Virology Poliomyelitis Virus Shedding Poliovirus Vaccines Infectious Diseases Treatment Outcome Pediatrics Perinatology and Child Health business Vaccine derived poliovirus
Zdroj:	The Pediatric infectious disease journal. 39(5)
ISSN:	1532-0987
Popis:	Pocapavir exhibits antiviral activity against both polio and nonpolio enteroviruses. There is limited experience of the use of this investigational drug in young children with enteroviral infection. We describe the successful clearance of prolonged immunodeficiency-associated vaccine-derived type 3 poliovirus infection by pocapavir in an infant with underlying X-linked agammaglobulinemia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aad3910125b41e55664a9c8ffb5ae3c https://pubmed.ncbi.nlm.nih.gov/32150007 Zobrazit plný text záznamu