Local antiseptic therapy for non-gonococcal urethritis: phase II study with Instillagel
| Autor: | F. Boeminghaus, H. Rübben, H.-P. Bastian, H. Sperling, G. Ludwig, B. Terhorst |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty medicine.drug_class Urology media_common.quotation_subject Antibiotics Non-gonococcal urethritis Colony Count Microbial Pain Urination Urine urologic and male genital diseases Gastroenterology Gonorrhea Antiseptic Urethra Internal medicine medicine Humans Urethritis media_common Antibacterial agent business.industry Chlorhexidine Lidocaine medicine.disease female genital diseases and pregnancy complications Surgery Drug Combinations medicine.anatomical_structure Treatment Outcome Anti-Infective Agents Local business |
| Zdroj: | World journal of urology. 20(1) |
| ISSN: | 0724-4983 |
| Popis: | Non-gonococcal urethritis (NGU) is conventionally treated with oral antibiotics. With this Phase II study, we investigated the action of a locally disinfecting substance, Instillagel, in symptomatic NGU. Instillation treatment was performed twice daily to 32 male patients with symptomatic NGU. To evaluate the therapeutic outcome, a smear was taken from the urethra and an urine examination was performed at baseline as well as at 5 and 8 days after the start of the treatment. Pain and micturition symptoms were determined by a questionnaire with analog scales taken before and after therapy. A pre/post comparison of the urethral smears of the patients with symptomatic NGU showed a significant difference (P |
| Databáze: | OpenAIRE |
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