Synthesis and Structural Characterization of Half-Sandwich Arene–Ruthenium(II) Complexes with Bis(imidazol-1-yl)methane, Imidazole and Benzimidazole
| Autor: | Denis G. Samsonenko, Andrei S. Potapov, Sergey V. Baykov, Lyubov S. Klyushova, Vadim P. Boyarskiy, Vladislava V. Matveevskaya, Dmitry I. Pavlov, Ekaterina A. Ermakova |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Benzimidazole
crystal structure 010405 organic chemistry chemistry.chemical_element 010402 general chemistry Transfer hydrogenation 01 natural sciences Medicinal chemistry benzimidazole 0104 chemical sciences Catalysis Ruthenium imidazole chemistry.chemical_compound chemistry Molecule Imidazole bis(imidazol-1-yl)methane Acetonitrile Bond cleavage Inorganic chemistry QD146-197 arene–ruthenium complexes |
| Zdroj: | Inorganics Volume 9 Issue 5 Inorganics, Vol 9, Iss 34, p 34 (2021) |
| ISSN: | 2304-6740 |
| DOI: | 10.3390/inorganics9050034 |
| Popis: | Mono- and binuclear arene–ruthenium(II) complexes with imidazole-containing ligands were prepared by the reaction of the ligands (L1 = bis(imidazole-1-yl)methane ImH = 1H-Imidazole BImH = 1H-Benzimidazole) with [(p-cym)Ru(µ-Cl)2]2 dimers. When bis(imidazole-1-yl)methane reacted with [(p-cym)Ru(µ-Cl)2]2 in methanol, a binuclear complex of the type [Ru2(L1)2(p-cym)2Cl2]Cl2 (2) with cyclic structure was synthesized, whereas by using acetonitrile as a solvent under the same reaction conditions, an unexpected C–N bond cleavage was observed, and a complex of formula [Ru(ImH)2(p-cym)Cl]Cl (1) with coordinated imidazole molecules was obtained. Another type of arene–ruthenium complex [Ru(BImH)(p-cym)Cl2] (3) was obtained by the reaction of benzimidazole and [(p-cym)Ru(µ-Cl)2]2. All compounds were characterized by spectral (FT-IR, NMR 1H, 13C) and single-crystal X-ray diffraction methods their catalytic activity in transfer hydrogenation and the cytotoxicity against MCF-7 and HepG2 cells were evaluated. |
| Databáze: | OpenAIRE |
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