Leiomyosarcoma After Liver Transplantation Is Unrelated to Epstein-Barr Virus: A Case Report
| Autor: | Y. Sun, Jianguo Zhang, Y.J. Gao, S. Zhou |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Leiomyosarcoma
Male Herpesvirus 4 Human medicine.medical_specialty medicine.medical_treatment Liver transplantation Malignancy medicine.disease_cause Gastroenterology Virus Cachexia Young Adult chemistry.chemical_compound Fatal Outcome Postoperative Complications Internal medicine medicine Humans Apatinib Transplantation business.industry Immunosuppression medicine.disease Epstein–Barr virus Tissue Donors Liver Transplantation body regions chemistry Surgery business |
| Zdroj: | Transplantation Proceedings. 52:2809-2812 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2020.06.023 |
| Popis: | Background De novo malignancy is a severe complication after liver transplantation (LT), but de novo leiomyosarcoma is extremely rare. Methods We reported de novo leiomyosarcoma occurring after LT. The patient’s status for Epstein-Barr virus was negative. The donor was a 21-year-old man with a central nervous system malignancy who underwent surgery. Three months later brain death occurred and his organs were donated. Results Leiomyosarcoma in the recipient was detected shortly after LT. It progressed after minimization of immunosuppression and apatinib therapy, and the patient died of cachexia 17 months after LT. Conclusions De novo leiomyosarcoma is a rare but serious event after LT, needing comprehensive management. |
| Databáze: | OpenAIRE |
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