Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma
Autor: | Marco Gatti, Riccardo Inchingolo, Michele Nardella, Davide Ippolito, Riccardo Faletti, Luigi Grazioli, Silvia Girolama Drago |
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Přispěvatelé: | Ippolito, D, Inchingolo, R, Grazioli, L, Drago, S, Nardella, M, Gatti, M, Faletti, R |
Rok vydání: | 2018 |
Předmět: |
Pathology
medicine.medical_specialty Cirrhosis Carcinoma Hepatocellular Hepatocellular carcinoma Perfusion Imaging Contrast media Liver Magnetic resonance Transarterial chemoembolization Contrast Media Perfusion scanning Multimodal Imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences Liver disease 0302 clinical medicine In vivo medicine Image Processing Computer-Assisted Humans Cirrhosi medicine.diagnostic_test Neovascularization Pathologic business.industry Non invasive Liver Neoplasms Gastroenterology Magnetic resonance imaging General Medicine medicine.disease Magnetic Resonance Imaging Functional imaging Treatment Outcome 030220 oncology & carcinogenesis Elasticity Imaging Techniques business |
Zdroj: | World journal of gastroenterology. 24(23) |
ISSN: | 2219-2840 |
Popis: | Magnetic resonance (MR) imaging of the liver is an important tool for the detection and characterization of focal liver lesions and for assessment of diffuse liver disease, having several intrinsic characteristics, represented by high soft tissue contrast, avoidance of ionizing radiation or iodinated contrast media, and more recently, by application of several functional imaging techniques (i.e., diffusion-weighted sequences, hepatobiliary contrast agents, perfusion imaging, magnetic resonance (MR)-elastography, and radiomics analysis). MR functional imaging techniques are extensively used both in routine practice and in the field of clinical and pre-clinical research because, through a qualitative rather than quantitative approach, they can offer valuable information about tumor tissue and tissue architecture, cellular biomarkers related to the hepatocellular functions, or tissue vascularization profiles related to tumor and tissue biology. This kind of approach offers in vivo physiological parameters, capable of evaluating physiological and pathological modifications of tissues, by the analysis of quantitative data that could be used in tumor detection, characterization, treatment selection, and follow-up, in addition to those obtained from standard morphological imaging. In this review we provide an overview of recent advanced techniques in MR for the diagnosis and staging of hepatocellular carcinoma, and their role in the assessment of response treatment evaluation. |
Databáze: | OpenAIRE |
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