Pediatric Expression of Mast Cell Activation Disorders
| Autor: | Lone Agertoft, Michael Boe Møller, Sigurd Broesby-Olsen, Melody C. Carter, Charlotte G. Mortz, Henrik Fomsgaard Kjaer, Carsten Bindslev-Jensen, Thomas Kielsgaard Kristensen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Urticaria Cell Degranulation Tryptases/metabolism Immunology Tryptase Proto-Oncogene Proteins c-kit/genetics Pathogenesis 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Food allergy Immunology and Allergy Medicine Humans Mast Cells Child Anaphylaxis biology Urticaria pigmentosa business.industry Mast cell activation Mastocytosis/genetics KIT mutations Anaphylaxis/genetics medicine.disease Mast cell Proto-Oncogene Proteins c-kit 030104 developmental biology medicine.anatomical_structure Mast Cells/physiology biology.protein Tryptases business Mastocytosis Mast cell activation disorders Urticaria/genetics |
| Zdroj: | Broesby-Olsen, S, Carter, M, Kjaer, H F, Mortz, C G, Møller, M B, Kristensen, T K, Bindslev-Jensen, C & Agertoft, L 2018, ' Pediatric Expression of Mast Cell Activation Disorders ', Immunology and Allergy Clinics of North America, vol. 38, no. 3, pp. 365-377 . https://doi.org/10.1016/j.iac.2018.04.009 |
| Popis: | Mast cell activation disorders is a term proposed to cover diseases and conditions related to activation of mast cells and effects of mast cell mediators. In its broadest sense, the term encompasses a wide range of diseases from allergic asthma to rhinoconjunctivitis, urticaria, food allergy, anaphylaxis, mastocytosis, and other conditions where MC activation is contributing to the pathogenesis. This article focuses on clinical presentations, challenges, and controversies in pediatric mastocytosis and gives an overview of current knowledge and areas in need of further research. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|