Hand Mirror Cells and Hypercalcemia: A Rare Presentation of Pediatric Acute Lymphoblastic Leukemia
| Autor: | Jorge Arredondo, Brian Leber, Stephanie Cox, Chantel Cacciotti, Uma H. Athale, Ereny Bassilious |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Oncology
Male medicine.medical_specialty Lymphoblastic Leukemia Adult population 03 medical and health sciences 0302 clinical medicine Pediatric Acute Lymphoblastic Leukemia hemic and lymphatic diseases Internal medicine Medicine Humans Hand mirror Lymphocytes Childhood Acute Lymphoblastic Leukemia business.industry Lymphoblast hemic and immune systems Hematology Precursor Cell Lymphoblastic Leukemia-Lymphoma medicine.disease Leukemia 030220 oncology & carcinogenesis Child Preschool Pediatrics Perinatology and Child Health Hypercalcemia Presentation (obstetrics) business 030215 immunology |
| Zdroj: | Journal of pediatric hematology/oncology. 42(3) |
| ISSN: | 1536-3678 |
| Popis: | Hand mirror cell (HMC) leukemia is a variant of acute lymphoblastic leukemia previously described in the adult population where lymphoblasts manifest distinctive hand mirror morphologic features. HMC has been previously identified in 23% of childhood acute lymphoblastic leukemia patients, but its prognostic significance in children is not well understood. Hypercalcemia is also uncommon in childhood leukemias. Hypercalcemia associated with HMC leukemia has not been previously reported. We report a 5-year-old boy with HMC B-lymphoblastic leukemia who presented with hypercalcemia. |
| Databáze: | OpenAIRE |
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