Parasites and asthma
| Autor: | Paron Dekumyoy, Wu Zhongdao, Lin Wuhao, Chen Ran, He Xujin, Lv Zhiyue |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.medical_treatment Regulatory B cells T-Lymphocytes Regulatory 03 medical and health sciences Mice Medical microbiology Immune system Th2 Cells Hygiene hypothesis medicine Parasitic Diseases Animals Humans Parasites Asthma B-Lymphocytes Regulatory General Veterinary Mechanism (biology) business.industry Macrophages General Medicine Dendritic Cells Macrophage Activation Th1 Cells medicine.disease respiratory tract diseases Interleukin-10 Interleukin 10 030104 developmental biology Infectious Diseases Cytokine Insect Science Immunology Parasitology business |
| Zdroj: | Parasitology research. 116(9) |
| ISSN: | 1432-1955 |
| Popis: | Nowadays, many studies have found low morbidity of asthma in epidemic areas of parasitic diseases, as shown by the hygiene hypothesis. It is obvious that some parasite infections can prevent asthma and studies have been carried out to clarify the mechanism of the preventive effect and search for the future asthmatic therapies. Previous findings have indicated that this mechanism may be related to the immune response switching from Th1 to Th2 and important cells induced by parasites, including the regulatory T cells, regulatory B cells, dendrite cells, and alternatively activated macrophages. Cytokine IL-10 also plays a nonredundant role in protection against allergic airway inflammation in asthma. This review focuses on the relationship between parasites and asthma, and the potential protection mechanism involved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink