Neurobiological mechanisms associated with facial affect recognition deficits after traumatic brain injury
Autor: | Brenna C. McDonald, Yang Wang, Michelle A. Keiski, John D. West, Dawn Neumann |
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Rok vydání: | 2015 |
Předmět: |
Adult
Male medicine.medical_specialty Traumatic brain injury Cognitive Neuroscience Emotions Poison control Audiology Neuropsychological Tests Facial recognition system 050105 experimental psychology Developmental psychology 03 medical and health sciences Behavioral Neuroscience Cellular and Molecular Neuroscience 0302 clinical medicine Neuroimaging Injury prevention Brain Injuries Traumatic medicine Humans 0501 psychology and cognitive sciences Radiology Nuclear Medicine and imaging Neuroradiology medicine.diagnostic_test 05 social sciences Neuropsychology Recognition Psychology Middle Aged medicine.disease Magnetic Resonance Imaging nervous system diseases Facial Expression Psychiatry and Mental health Affect nervous system Neurology Face Female Neurology (clinical) Functional magnetic resonance imaging Psychology Facial Recognition 030217 neurology & neurosurgery |
Zdroj: | Brain imaging and behavior. 10(2) |
ISSN: | 1931-7565 |
Popis: | The neurobiological mechanisms that underlie facial affect recognition deficits after traumatic brain injury (TBI) have not yet been identified. Using functional magnetic resonance imaging (fMRI), study aims were to 1) determine if there are differences in brain activation during facial affect processing in people with TBI who have facial affect recognition impairments (TBI-I) relative to people with TBI and healthy controls who do not have facial affect recognition impairments (TBI-N and HC, respectively); and 2) identify relationships between neural activity and facial affect recognition performance. A facial affect recognition screening task performed outside the scanner was used to determine group classification; TBI patients who performed greater than one standard deviation below normal performance scores were classified as TBI-I, while TBI patients with normal scores were classified as TBI-N. An fMRI facial recognition paradigm was then performed within the 3T environment. Results from 35 participants are reported (TBI-I = 11, TBI-N = 12, and HC = 12). For the fMRI task, TBI-I and TBI-N groups scored significantly lower than the HC group. Blood oxygenation level-dependent (BOLD) signals for facial affect recognition compared to a baseline condition of viewing a scrambled face, revealed lower neural activation in the right fusiform gyrus (FG) in the TBI-I group than the HC group. Right fusiform gyrus activity correlated with accuracy on the facial affect recognition tasks (both within and outside the scanner). Decreased FG activity suggests facial affect recognition deficits after TBI may be the result of impaired holistic face processing. Future directions and clinical implications are discussed. |
Databáze: | OpenAIRE |
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