The testis-specific transcript (ferT) of the tyrosine kinase FER is expressed during spermatogenesis in a stage-specific manner
| Autor: | Eli Keshet, Ahuva Itin, Uri Nir, K Fischman |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
Transcription Genetic Histocytochemistry Nucleic Acid Hybridization In situ hybridization Cell Biology Biology Protein-Tyrosine Kinases Molecular biology Gene Expression Regulation Enzymologic Nucleic acid thermodynamics Mice Prophase Meiosis Gene expression Testis Animals RNA Messenger Spermatogenesis Gene Tyrosine kinase Molecular Biology Research Article |
| Zdroj: | Molecular and cellular biology. 10(9) |
| ISSN: | 0270-7306 |
| Popis: | ferT is a testis-specific transcript of FER encoding a truncated version of the potential tyrosine kinase. Using in situ hybridization analysis, we found that ferT was transiently expressed during spermatogenesis and that expression was restricted to spermatocytes at the pachytene stage of meiotic prophase. This pattern of expression is unprecedented by other tyrosine kinases and suggests a role for ferT in a particular stage of spermatogenesis. |
| Databáze: | OpenAIRE |
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