Predicting the risk of early atherosclerotic disease development in children after repair of aortic coarctation
| Autor: | Andreas Alexander Meyer, Masood S. Joharchi, Peter Schuff-Werner, Günther Kundt, Gustav Steinhoff, Wolfgang Kienast |
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| Rok vydání: | 2004 |
| Předmět: |
Male
Reoperation medicine.medical_specialty Adolescent Brachial Artery Arteriosclerosis Vasodilation Aortic Coarctation Postoperative Complications Risk Factors Internal medicine medicine Humans Risk factor Child Vascular disease business.industry Atherosclerotic disease Prognosis medicine.disease Control subjects Surgery Carotid Arteries Blood pressure El Niño Intima-media thickness Echocardiography Regional Blood Flow Case-Control Studies Exercise Test cardiovascular system Cardiology Female Tunica Intima Cardiology and Cardiovascular Medicine business |
| Zdroj: | European Heart Journal. 26:617-622 |
| ISSN: | 1522-9645 0195-668X |
| Popis: | Aims Increased cardiovascular morbidity is manifested a long time after the repair of aortic coarctation (CoA). By way of impaired flow-mediated vasodilation (FMD) and increased intima media thickness (IMT), surrogate parameters of atherosclerosis, cardiovascular risk factors (RFs) can be correlated with early vascular wall changes in children. This study investigated whether changes in arterial wall function and morphology are detectable in children after coarctation repair. Methods and results We examined 28 children after successful repair of CoA vs. 30 control subjects. All children underwent identical screening, with a broad RF profile and FMD/IMT measurements. CoA-children presented significantly ( P |
| Databáze: | OpenAIRE |
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