Amiodarone-induced loculated pleural effusion without pulmonary parenchymal involvement: A case report and literature review
Autor: | Ashraf Jmeian, Fayez Shamoon, Mohammad Thawabi, Amer Hawatmeh, Hamid Shaaban |
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Rok vydání: | 2017 |
Předmět: |
Weakness
medicine.medical_specialty Pleural effusion Pulmonary toxicity Amiodarone Case Report 030204 cardiovascular system & hematology Gastroenterology General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine pleural effusion Internal medicine medicine 030212 general & internal medicine Adverse effect pulmonary toxicity Lung business.industry Thyroid General Medicine medicine.disease respiratory tract diseases medicine.anatomical_structure Anesthesia Toxicity medicine.symptom business medicine.drug |
Zdroj: | Journal of Natural Science, Biology, and Medicine |
ISSN: | 0976-9668 |
DOI: | 10.4103/0976-9668.198345 |
Popis: | Amiodarone is an extremely effective antiarrhythmic drug that is known to cause many adverse effects such as pulmonary, thyroid, and liver toxicities. Of these, pulmonary toxicity is most serious. Pulmonary toxicity can present as interstitial pneumonitis, organizing pneumonia, pulmonary nodules and masses, and very rarely pleural effusions. We present a case of a 73-year-old male who presented with progressive exertional dyspnea, nonproductive cough, generalized fatigue, and weakness. He was found to have multiorgan toxicity secondary to long-term treatment with high doses of amiodarone. This case illustrates that amiodarone may cause toxicity involving multiple organs simultaneously in patients receiving long-term therapy and represents the first reported case of amiodarone-induced loculated pleural effusion without associated lung parenchymal involvement. |
Databáze: | OpenAIRE |
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