[Achalasia and Guillain-Barré syndrome]
| Autor: | Michaela Müller, V. F. Eckardt, H. Graap, B. Schrank |
|---|---|
| Jazyk: | němčina |
| Rok vydání: | 2009 |
| Předmět: |
Male
Chest Pain Manometry Achalasia Myenteric Plexus Botulinum toxin injection Guillain-Barre Syndrome Autoimmune Diseases otorhinolaryngologic diseases medicine Humans In patient Botulinum Toxins Type A Myenteric plexus Neurologic Examination Guillain-Barre syndrome business.industry Gastroenterology Middle Aged medicine.disease Dysphagia Ganglion Esophageal Achalasia medicine.anatomical_structure Solid food Anesthesia Nerve Degeneration Esophagoscopy medicine.symptom business Deglutition Disorders |
| Zdroj: | Zeitschrift fur Gastroenterologie. 47(11) |
| ISSN: | 1439-7803 |
| Popis: | A 47-year-old patient with a history of Guillain-Barre syndrome three years prior to evaluation and a severe persisting sensory neuronopathy, complained of dysphagia especially for solid food. He also had severe, intermittent retrosternal pain. Radiological and manometric studies showed the typical features of achalasia. Treatment with botulinum toxin injection improved the dysphagia but not the retrosternal pain. An autoimmune response triggered by an infection is discussed as one possible cause of ganglion cell degeneration within the myenteric plexus in patients with achalasia. Such a hypothesis is supported by our observation showing the simultaneous occurrence of achalasia, sensory neuronopathy, and Guillain-Barre syndrome. |
| Databáze: | OpenAIRE |
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