Ganglioside containing nano-proteoliposome dampens myeloid-derived suppressor cells function and ability to cross-present tumor antigens: a new approach to recover CTL function on tumor bearing individuals

Autor:	Circe Mesa, Maura Rabade-Chediak, Liliana Oliver, Luis E. Fernández, Audry Fernández, Leslie Pérez, Rydell Alvarez, Arletty Hernández
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Pharmacology Cancer Research Ganglioside business.industry Immunology Tumor antigen CTL Oncology Antigen Poster Presentation Myeloid-derived Suppressor Cell Cancer research Molecular Medicine Immunology and Allergy Medicine Tumor growth Myelopoiesis business
Zdroj:	Journal for Immunotherapy of Cancer
ISSN:	2051-1426
Popis:	Meeting abstracts A perturbation of normal myelopoiesis, as a consequence of tumor growth and development; leads to the proliferation and accumulation of myeloid derived suppressor cells (MDSC), which impair T-cell functions reinforcing tolerance to tumor antigens (TA). For these reasons it is
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a60aad6fe82e3eab2b130c3e08bd5c3 http://europepmc.org/articles/PMC3991200 Zobrazit plný text záznamu