Metal‐Free Photoredox‐Catalyzed Hydrodefluorination of Fluoroarenes Utilizing Amide Solvent as Reductant

Autor:	Nobuharu Iwasawa, Kazuya Yamashita, Naoyuki Toriumi
Rok vydání:	2021
Předmět:	Organic Chemistry General Chemistry Amides Combinatorial chemistry Catalysis Solvent chemistry.chemical_compound Hydrodefluorination Metal free chemistry Metals Reducing Agents Amide Solvents Photocatalysis
Zdroj:	Chemistry – A European Journal. 27:12635-12641
ISSN:	1521-3765 0947-6539
Popis:	A metal-free photoredox-catalyzed hydrodefluorination of fluoroarenes was achieved by using N,N,N',N'-tetramethyl-para-phenylenediamine (1) as a strong photoreduction catalyst. This reaction was applicable not only to electron-rich monofluoroarenes but also to polyfluoroarenes to afford non-fluorinated arenes. The experimental mechanistic studies indicated that the amide solvent NMP plays an important role for regeneration of the photocatalyst, enabling additive-free photoreduction catalysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5e3dd490d86b0ec413cd31afccb89a https://doi.org/10.1002/chem.202101813 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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