The effect of mental health conditions on the use of oral anticoagulation therapy in patients with atrial fibrillation: the FinACAF study
| Autor: | Konsta Teppo, Janne Kinnunen, Juha Hartikainen, Miika Linna, Fausto Biancari, Aapo L. Aro, Olli Halminen, Mika Lehto, Jukka Putaala, Jari Haukka, Paula Tiili, K.E. Juhani Airaksinen, Jussi Jaakkola, Pirjo Mustonen |
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| Přispěvatelé: | University of Turku, University of Helsinki, Department of Industrial Engineering and Management, Turku University Hospital, Helsinki University Central Hospital, Kuopio University Hospital, Aalto-yliopisto, Aalto University, HUS Heart and Lung Center, HUS Neurocenter, Clinicum, Department of Neurosciences, Neurologian yksikkö, Department of Public Health, Jari Haukka / Principal Investigator |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Male
medicine.medical_specialty DISORDERS Administration Oral 030204 cardiovascular system & hematology WARFARIN 03 medical and health sciences Anticoagulation 0302 clinical medicine PEOPLE Internal medicine Psychiatric medication Humans Medicine 030212 general & internal medicine Bipolar disorder Medical prescription Depression (differential diagnoses) Aged RISK OUTCOMES business.industry Depression Health Policy Incidence (epidemiology) Anticoagulants Atrial fibrillation CARE medicine.disease 3. Good health Stroke LIFE Inequality Schizophrenia 3121 General medicine internal medicine and other clinical medicine Female Mental health Cardiology and Cardiovascular Medicine business Anxiety disorder |
| Popis: | Aims Little is known about the effects of mental health conditions (MHCs) on the utilization of oral anticoagulation (OAC) therapy in atrial fibrillation (AF) patients. We aimed to assess whether MHCs affect initiation of OAC therapy among AF patients with special focus on non-vitamin K antagonist oral anticoagulants (NOACs). Methods and results The Finnish AntiCoagulation in Atrial Fibrillation (FinACAF) registry included all 239 222 patients diagnosed with incident AF during 2007–18 in Finland identified from national registries covering primary to tertiary care and drug purchases. Patients with previous depression, bipolar disorder, anxiety disorder, or schizophrenia diagnosis or a fulfilled psychiatric medication prescription within the year preceding the AF diagnosis were classified to have any MHC. The main outcome was OAC initiation, defined as first fulfilled OAC prescription after AF diagnosis. The patients’ mean age was 72.7 years and 49.8% were female. The prevalence of any MHC was 19.9%. A lower proportion of patients with any MHC compared with those without MHCs were initiated on OAC therapy (64.9% vs. 73.3%, P Conclusion MHCs are common among AF patients, and they are associated with a lower rate of OAC initiation even during the NOAC era. |
| Databáze: | OpenAIRE |
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