Pathogenicity of facultative and obligate anaerobic bacteria in monoculture and combined with either Prevotella intermedia or Prevotella nigrescens
Autor: | M. de Uzeda, José F. Siqueira, Kenio Costa de Lima, Fernando A.C. Magalhães |
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Rok vydání: | 1999 |
Předmět: |
Microbiology (medical)
Male Immunology Prevotella Virulence Microbiology Prevotella intermedia Bacteria Anaerobic Mice Prevotella nigrescens stomatognathic system Animals Porphyromonas General Dentistry Bacteroidaceae Ecosystem Facultative biology Obligate Dental Pulp Diseases biology.organism_classification Abscess stomatognathic diseases Disease Models Animal Anaerobic bacteria Bacteria |
Zdroj: | Oral microbiology and immunology. 13(6) |
ISSN: | 0902-0055 |
Popis: | The pathogenicity of obligate and facultative anaerobic bacteria commonly found in endodontic infections was tested using a mouse model. The capacity of inducing abscesses was evaluated seven days after subcutaneous injection of the bacteria in pure culture and in combinations with either Prevotella intermedia or Prevotella nigrescens. Nine of the fifteen bacterial strains tested were pathogenic in pure culture. No statistically significant differences were detected between these strains in pure culture and in mixtures with either P. intermedia or P. nigrescens. Synergism between the bacterial strains was only apparent when associating Porphyromonas endodontalis with P. intermedia or P. nigrescens. Histopathological examination of tissue sections from induced abscesses revealed an acute inflammatory reaction, dominated by polymorphonuclear leukocytes. Sections from the control group using sterile medium showed no evidence of inflammatory reaction. |
Databáze: | OpenAIRE |
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