Assessment of impairment/disability due to occupational asthma through a multidimensional approach
| Autor: | Jean Luc Malo, Guillaume Lacoste, Kim L. Lavoie, H Ghezzo, Jocelyne L'Archevêque, Mona-Rita Yacoub, Catherine Lemière, S. Daigle |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Severity of Illness Index Occupational medicine Disability Evaluation Quality of life (healthcare) Risk Factors Occupational Exposure Surveys and Questionnaires Internal medicine Severity of illness medicine Humans Depression (differential diagnoses) Asthma Inflammation Analysis of Variance business.industry Sputum Middle Aged medicine.disease Respiratory Function Tests respiratory tract diseases Occupational Diseases Quality of Life Physical therapy Regression Analysis Anxiety Female medicine.symptom business Occupational asthma |
| Zdroj: | European Respiratory Journal. 29:889-896 |
| ISSN: | 1399-3003 0903-1936 |
| DOI: | 10.1183/09031936.00127206 |
| Popis: | Subjects with occupational asthma (OA) are often left with permanent sequelae after removal from exposure, and assessing their impairment/disability should utilise various tools. The aim of the present study was to examine whether: 1) assessment of inflammation in induced sputum is relevant to impairment; and 2) use of questionnaires on quality of life and psychological factors can be useful for the evaluation of disability. In total, 40 subjects were prospectively assessed for permanent impairment/disability due to OA 2 yrs after cessation of exposure. Impairment was assessed as follows: 1) need for asthma medication; 2) asthma severity; 3) airway calibre and responsiveness; and 4) degree of inflammation in induced sputum. Disability was assessed according to quality of life and psychological distress. There was a significant improvement in airway responsiveness and inflammation from diagnosis to the present assessment. Sputum eosinophils > or =2% and neutrophils >60% were present in eight (20%) and 12 (30%) out of all subjects, respectively, one or the other feature being the only abnormalities in 15% of subjects. Quality of life was moderately affected and there was a prevalence of depression and anxiety close to 50%. In the assessment of subjects with occupational asthma, information on airway inflammation and psychological impacts are relevant to the assessment of impairment/disability, although these findings need further investigation. |
| Databáze: | OpenAIRE |
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