Ductal Adenocarcinoma of the Pancreas
| Autor: | Giuseppe Zamboni, Anna Pesci, Paola Castelli, Giuseppe Bogina, Laura Bortesi |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases business.industry Clinical manifestation medicine.disease Gastroenterology digestive system diseases Pathology and Forensic Medicine medicine.anatomical_structure Internal medicine Pancreatic cancer Exocrine pancreas medicine Pancreatitis Surgery Ductal adenocarcinoma Differential diagnosis Pancreas business Survival rate |
| Zdroj: | Surgical Pathology Clinics. 4:487-521 |
| ISSN: | 1875-9181 |
| DOI: | 10.1016/j.path.2011.03.007 |
| Popis: | Pancreatic ductal adenocarcinoma (PDAC) and its variants comprise between 80% and 90% of all tumors of the exocrine pancreas. Because of its silent course, late clinical manifestation, and rapid growth, it is considered a silent killer. Only 10% to 15% of cases are resectable and the 5-year survival rate remains lower than 5%. The differential diagnosis between PDAC and chronic pancreatitis is a challenge for pathologists. This article provides a guide for pathologic evaluation of PDAC specimens with the macroscopic and microscopic features of common PDAC and its variants and discusses the differential diagnosis and morphologic and immunophenotypical prognostic parameters. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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