Development of criteria for investigation of periapical tissue from root-filled teeth
| Autor: | Noushin Danesh, Helena Fransson, Anna Ljunggren, Eva Wolf |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Tooth Nonvital medicine.diagnostic_test business.industry Periapical Tissue Dentistry 030206 dentistry General Medicine Middle Aged Root Canal Therapy 03 medical and health sciences 0302 clinical medicine Root Canal Obturation Biopsy Humans Medicine Female Periapical tissue business General Dentistry Periapical Periodontitis 030217 neurology & neurosurgery Aged |
| Zdroj: | Acta Odontologica Scandinavica. 77:269-274 |
| ISSN: | 1502-3850 0001-6357 |
| DOI: | 10.1080/00016357.2018.1538534 |
| Popis: | To develop and assess a set of criteria to grade inflammation including relative area of inflammation in periapical lesions in endodontically treated teeth.A set of criteria was developed, encompassing data on: Lymphocytes, denoting chronic inflammation, were graded 0 (occasional) to 4 (heavy/dense inflammation). Polymorphonuclear cells, denoting acute inflammation, were graded 0 (none) to 2 (many). The third parameter, area of inflammation, that is, the relative area of the specimen that was inflamed, was graded 0 (none) to 4 (76-100%). The criteria were tested on 199 consecutive biopsies from 180 patients (aged 31-75 years). Information about symptoms was retrieved from the referrals. Mann-Whitney's U-test was used to calculate possible differences in average values for the histopathological variables in the two groups of patients: symptomatic or asymptomatic.Using the criteria, varying grades of inflammation were seen in the biopsies. The majority showed few or no PMN cells. There was a correlation between symptoms and the extent of infiltration of lymphocytes and plasma cells (p = .001), PMN cells (p .001) and the area of inflammation (p = .002): biopsies from the asymptomatic patients exhibited less pronounced and relatively smaller areas of inflammation.Using the criteria on a specific selection of root-filled teeth with persisting apical periodontitis, periapical inflammation was common, but varied in extent and severity. The inflammation was less pronounced and affected a relatively smaller area in asymptomatic teeth, although outliers in both directions were identified. |
| Databáze: | OpenAIRE |
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