Biofunctional hybrid materials: bimolecular organosilane monolayers on FeCr alloys
| Autor: | Leila Costelle, Markku Hannula, M. Hirsimäki, Mika Valden, Ergo Nõmmiste, Jenni Leppiniemi, Leena Vuori, Kimmo Lahtonen, Vesa P. Hytönen |
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| Přispěvatelé: | Tampere University, Research group: Surface Science, Optoelectronics Research Centre, Institute of Biomedical Technology, Department of Clinical Chemistry, Multi-scaled biodata analysis and modelling (MultiBAM), Frontier Photonics |
| Rok vydání: | 2014 |
| Předmět: |
Streptavidin
Materials science Bioengineering Nanotechnology 02 engineering and technology 010402 general chemistry 114 Physical sciences 01 natural sciences chemistry.chemical_compound X-ray photoelectron spectroscopy Monolayer General Materials Science Reactivity (chemistry) Electrical and Electronic Engineering Derivatization Silanes Mechanical Engineering 221 Nanotechnology General Chemistry 021001 nanoscience & nanotechnology 0104 chemical sciences chemistry Chemical engineering Mechanics of Materials 216 Materials engineering 1182 Biochemistry cell and molecular biology Surface modification 0210 nano-technology Hybrid material |
| Zdroj: | Nanotechnology. 25:435603 |
| ISSN: | 1361-6528 0957-4484 |
| DOI: | 10.1088/0957-4484/25/43/435603 |
| Popis: | Hybrid organic-inorganic interfaces are the key to functionalization of stainless steel (SS). We present a solution-based deposition method for fabricating uniform bimolecular organosilane monolayers on SS and show that their properties and functionalities can be further developed through site-specific biotinylation. We correlate molecular properties of the interface with its reactivity via surface sensitive synchrotron radiation mediated high-resolution photoelectron spectroscopy (HR-PES) and chemical derivatization (CD), and we demonstrate specific bonding of streptavidin proteins to the hybrid interface. The method facilitates efficient growth of uniform bimolecular organosilane monolayers on SS under ambient conditions without the need to prime the SS surface with vacuum-deposited inorganic buffer layers. The obtained insights into molecular bonding, orientation, and behaviour of surface-confined organofunctional silanes on SS enable a new generic approach to functionalization of SS surfaces with versatile nanomolecular organosilane layers. |
| Databáze: | OpenAIRE |
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