Drotaverine hydrochloride versus hyoscine-N-butylbromide in augmentation of labor
| Autor: | Bindiya Gupta, Vimala Nellore, Suneeta Mittal |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Cervical dilation law.invention Randomized controlled trial Pregnancy law Papaverine Butylscopolammonium Bromide Humans Medicine Prospective Studies Prospective cohort study Hyoscine n-butylbromide Labor Obstetric business.industry Parasympatholytics Obstetrics and Gynecology General Medicine medicine.disease Anesthesia Female business Drotaverine medicine.drug DROTAVERINE HYDROCHLORIDE |
| Zdroj: | International Journal of Gynecology & Obstetrics. 100:244-247 |
| ISSN: | 0020-7292 |
| DOI: | 10.1016/j.ijgo.2007.08.020 |
| Popis: | Objectives: To study and compare the efficacy and side effects of drotaverine hydrochloride and hyoscine-N-butylbromide in the augmentation of labor. Methods: A prospective randomized trial of 150 women in active labor included 50 women given drotaverine (group 1), 50 women given hyoscine-N-butylbromide (group 2), and 50 women given no medication (group 3). Duration of labor, rate of cervical dilation, mode of delivery, side effects, and neonatal outcome were compared among the groups. Results: The mean duration of the active phase of labor was 4.48 ± 2.26 h, 3.9 ± 2.42 h, and 3.6 ± 2.07 h in groups 1, 2, and 3, respectively. The mean rate of cervical dilation was 2.6 cm/h, 2.4 cm/h, and 2.5 cm/h, respectively. The differences were not statistically significant. There was no difference in the duration of the second and third stages of labor. No adverse maternal or fetal outcomes were noted. Conclusion: Drotaverine hydrochloride and hyoscine-N-butylbromide do not have a role in augmentation of labor. |
| Databáze: | OpenAIRE |
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