Effects of 1 MHz Therapeutic Ultrasound on Limb Blood Flow and Microvascular Reactivity: A Randomized Pilot Trial
| Autor: | Manuel Marchena Gómez, Alvaro N. Gurovich, Megan Waters, Jozelyn Rascon, Branko Miljkovic |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Health
Toxicology and Mutagenesis medicine.medical_treatment Pilot Projects Placebo Article Forearm Medicine Effective treatment Humans blood flow Cross-Over Studies Therapeutic ultrasound business.industry Pilot trial Public Health Environmental and Occupational Health Hemodynamics Repeated measures design Blood flow body regions medicine.anatomical_structure Regional Blood Flow therapeutic ultrasound Anesthesia Forearm blood flow microvascular function business |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 18 Issue 21 International Journal of Environmental Research and Public Health, Vol 18, Iss 11444, p 11444 (2021) |
| ISSN: | 1660-4601 |
| DOI: | 10.3390/ijerph182111444 |
| Popis: | A randomized, double-blind, placebo-controlled, cross-over study where continuous therapeutic ultrasound (CUS at 0.4 W/cm2), pulsed therapeutic ultrasound (PUS at 20% duty cycle, 0.08 W/cm2), both at 1 MHz, and placebo (equipment on, no energy provided) were randomized and applied over the forearm of the non-dominant arm for 5 min in 10 young, healthy individuals. Absolute and peak forearm blood flow (FBF) were measured via Venous Occlusion Plethysmography. FBF was measured before, halfway, and after (immediately and 5 min after) the therapeutic ultrasound (TUS) intervention. Post-ischemic peak FBF was measured 10 min before and 10 min after the TUS intervention. A two-way repeated measures ANOVA (group × time) was selected to assess differences in FBF before, during, and after TUS treatment, and for peak FBF before and after TUS treatment. FBF increased 5 min after TUS in CUS compared to placebo (2.96 ± 1.04 vs. 2.09 ± 0.63 mL/min/100 mL of tissue, p < 0.05). PUS resulted in the greatest increase in Peak FBF at 10 min after US (Δ = 3.96 ± 2.02 mL/min/100 mL of tissue, p = 0.06). CUS at 1 MHz was an effective treatment modality for increasing FBF up to 5 min after intervention, but PUS resulted in the greatest increase in peak FBF at 10 min after intervention. |
| Databáze: | OpenAIRE |
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