Ramucirumab-related Oral Pyogenic Granuloma: A Report of Two Cases
| Autor: | Yasuyuki Michi, Tadanobu Aragaki, Hisashi Hosaka, Tetsuya Yoda, Yasuyuki Fukai, Nobuyoshi Tomomatsu, Misa Iijima |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Angiogenesis 030204 cardiovascular system & hematology Antibodies Monoclonal Humanized Ramucirumab Lesion 03 medical and health sciences 0302 clinical medicine Oral pyogenic granuloma Tongue Internal Medicine medicine Humans Granuloma Pyogenic Aged Pyogenic granuloma business.industry Upper lip Mouth Mucosa Cancer General Medicine Middle Aged medicine.disease Dermatology Lip stomatognathic diseases medicine.anatomical_structure 030211 gastroenterology & hepatology medicine.symptom business |
| Zdroj: | Internal medicine (Tokyo, Japan). 60(16) |
| ISSN: | 1349-7235 |
| Popis: | Pyogenic granuloma (PG) is a granulomatous elevated lesion that occurs on the skin and mucous membranes. We herein report two cases of intra-oral PG that developed during the administration of ramucirumab for gastric cancer. Case 1 involved a 55-year-old man with a 6-mm tumor on the right tongue, and case 2 involved a 67-year-old man with a 5-mm tumor on the upper lip. The imbalance in angiogenesis caused by ramucirumab and the deterioration in the local oral environment were suggested to have caused the PG. Medical and dental collaboration is essential during the administration of ramucirumab. |
| Databáze: | OpenAIRE |
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