Total Antioxidant Capacity and Antioxidant Enzymes in Serum, Saliva, and Gingival Crevicular Fluid of Preeclamptic Women With and Without Periodontal Disease
| Autor: | Abubekir Eltas, Yasin Cicek, Varol Canakci, Abdulkadir Yildirim, Cenk Fatih Canakci, Humeyra Canakci |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Saliva Antioxidant Pregnancy Trimester Third medicine.medical_treatment Dental Plaque Physiology Blood Pressure Gestational Age Antioxidants Preeclampsia Superoxide dismutase chemistry.chemical_compound Pre-Eclampsia Pregnancy Malondialdehyde Periodontal Attachment Loss medicine Birth Weight Humans Periodontal Pocket Periodontal Diseases chemistry.chemical_classification Glutathione Peroxidase biology Superoxide Dismutase business.industry Superoxide Glutathione peroxidase Body Weight Infant Newborn Free Radical Scavengers Gingival Crevicular Fluid medicine.disease Pregnancy Complications chemistry Immunology biology.protein Periodontics Female Gingival Hemorrhage business Peroxidase |
| Zdroj: | Journal of Periodontology. 78:1602-1611 |
| ISSN: | 1943-3670 0022-3492 |
| DOI: | 10.1902/jop.2007.060469 |
| Popis: | The aim of this study was to investigate the total antioxidant capacity, superoxide dismutase and glutathione peroxidase activities, and malondialdehyde levels in serum, saliva, and gingival crevicular fluid (GCF) in preeclamptic and normotensive pregnant women with and without periodontal disease.Forty pregnant women, consisting of 10 preeclamptic subjects with periodontal disease, 10 preeclamptic periodontally healthy subjects, 10 normotensive subjects with periodontal disease, and 10 normotensive periodontally healthy subjects, were included in this study. After clinical measurement and samplings, total antioxidant capacity, superoxide dismutase, glutathione peroxidase activities, and malondialdehyde levels in serum, saliva, and GCF of preeclamptic and normotensive pregnant women were determined, and the data were tested by non-parametric tests. Total antioxidant capacity of the clinical samples was measured using a novel automated colorimetric measurement method. Superoxide dismutase and glutathione peroxidase activities and malondialdehyde levels were determined spectrophotometrically.Superoxide dismutase and glutathione peroxidase activities in GCF and serum and total antioxidant capacity in saliva, GCF, and serum were the lowest in preeclamptic women with periodontal disease. However, serum and GCF levels of malondialdehyde were the highest in this group of pregnant women.Systemic and local antioxidant and total antioxidant capacities are affected by periodontal disease in addition to the impact of preeclamptic status. Similar comments may be made for the increases in systemic and local malondialdehyde levels. |
| Databáze: | OpenAIRE |
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